MDMA and weed: similarities, differences and interactions

Another important factor that is generally unstudied would be what cannabis chemovar is being consumed. American scientists in the 1950s and 1960s set out to determine how LSD affected users. Try as they might, they couldn’t quite ascertain “standard effects,” i.e. how a drug should or typically behaves.

  1. That’s why we never suggest people consume cannabis when working with a psychedelic substance for the first time—it increases the likelihood of the experience being overwhelming.
  2. Mixing weed and ecstasy may sound like a good time, but the reality is quite different.
  3. However, when acid was first being explored as a psychiatric tool in the ‘50s and ‘60s, many clinical trials combined LSD with an antidepressant.

Cannabis and LSD drug interactions

We simply can’t sit back and let Americans continue to sit in silent suffering trying to battle mental health issues within a broken health care system, all while knowing that effective alternatives exist. We stand for the how to make yourself pee 9 remedies and techniques sacred, at-home, ceremonial use of psychedelics for consciousness exploration, which we believe to be a fundamental human right. Perhaps more importantly, consider if cannabis will add or detract from your intention.

MDMA (Ecstasy) Abuse Research Report

There’s some evidence to suggest that ecstasy isn’t traditionally addictive, but regular users may develop an attachment to the behavioral aspects of use. Marijuana is among the most commonly used substances in the United States, especially as legal use continues to become more widespread. Around 12 percent of the adult population smokes pot, a statistic that rises to 22 percent among those 18 to 29. These benefits are unproven, however, and more research is needed to fully understand the complex interactions between these two very different drugs. Cannabis has many potential therapeutic benefits and can be used legally with a valid medical marijuana card.

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Despite having served in Iraq during the first months of the war, Chris had never felt entitled to the PTSD label. To treat his symptoms, which included insomnia, recurring nightmares, and hypervigilance, therapists prescribed Chris an antidepressant, administered cognitive behavioral therapy, and taught him to meditate. He was grateful for those tools, which helped stabilize his mood somewhat. In support of its application, Lykos Therapeutics, formerly known as Multidisciplinary Association for Psychedelic Studies (MAPS), studied the party drug MDMA, more commonly called ecstacy or molly, in two late-stage studies. MDMA causes a surge of serotonin, after which the body will experience a depletion of this “feel-good” neurotransmitter. These effects may be due to MDMA alone, or to the combination of MDMA use with other drugs.

Outlook for people who use MDMA and alcohol together

Tripping on acid can be one of the most profound experiences in some people’s lives. Just a tiny speck of LSD (scientifically known as lysergic acid diethylamide) will trigger an experience that can last 12 hours, depending on the dose and purity. It gives users a teeth-rattling “trip” packed with amplified colors that ripple and flow across their distorted perception of time and space. Ego, or the sense of self, can disintegrate into the soul’s ectoplasmic goo. There is a clear overlap of pharmacology between cannabis and psychedelics. Both are being considered as novel treatments for conditions that currently lack adequate effective therapies like anxiety, depression, and PTSD.

The effects and safety of this combination are highly unpredictable and may lead to undesirable consequences. While these substances work in different ways, both MDMA and cannabis use have potent effects on perception and can cause serious and lasting changes to mental health, especially when used recklessly or chronically. In general, experienced cannabis users tend to have a better experience combining with psychedelics when compared to novices. Alternatively, novices can get overwhelmed when introducing cannabis to the psychedelic experience as it increases intensity and duration. It’s important to keep in mind the complexities of cannabinoid and terpene profiles and how they modulate cannabis highs.

Yes, weed can be laced or contaminated with MDMA or other substances. This can occur in illicit drug markets where the purity and quality of substances are not regulated. When marijuana is intentionally adulterated or cut” with other drugs, such as MDMA, it is typically done to enhance the effects of the cannabis or to deceive consumers. Although some individuals may choose to mix MDMA and weed, it is crucial to recognize that this practice can carry significant health risks.

When in the body, marijuana often produces a relaxed and euphoric sensation. Recreational ecstasy tablets are often counterfeited and adulterated with a wide range of other substances ranging from benign or toxic fillers to drugs ecstasy users would not likely take. In many cases, MDMA users who are denied access to water or exposed to high temperatures have suffered heat stroke, seizures, and other adverse effects that can, unfortunately, be lethal magic mushroom side effects without immediate medical intervention. Marijuana and ecstasy are both relatively common substances of abuse among young people, especially in certain scenes like music festivals and raves. So called “soft” drugs like marijuana and ecstasy are generally less habit-forming (addictive) than “hard” drugs like methamphetamine, cocaine, and heroin. At Psychedelic Passage, we offer professional 1-on-1 guidance and companionship on your journey of healing.

Peterson also cautions consumers to be careful when using cannabis with other non-prescription substances that affect mood, awareness, thoughts, feelings or behavior. CBD inhibits the metabolic pathway used by these drugs, similar to other natural compounds like grapefruit or St. John’s Wort. When this pathway is suppressed, medications take longer to be metabolized or fatal fix: how an opioid overdose shuts down your body broken down by the body, so levels of the drug can accumulate and circulate in the blood for longer. Beyond these four major classes of drugs, there are other medications and compounds with which cannabis can interact. “There’s little data at all for mixing hallucinogens with cannabis, but years of common experience has not shown any overt problems,” added Tishler.

Both alcohol and MDMA use during pregnancy pose risks to mother and baby. Lately, researchers have been exploring whether cannabis and opioids can be safely used together. “We do know that CBD will interact with benzodiazepines by increasing their blood levels,” said Tishler. “THC’s drug-drug interactions are typically pharmacodynamic, meaning they change how [another] drug affects us. CBD’s drug interactions are typically pharmacokinetic, meaning they alter how other medication is broken down,” said Peterson. It can also make an LSD trip feel longer and more intense, which isn’t always a good thing.

CBD serves almost as a balance for the effects of THC by producing feelings of relaxation and pain reduction. Although many people believe that marijuana is harmless, this isn’t entirely true. Too much THC can cause scary and unpredictable mind-altering effects, including psychosis. Marijuana is made up of dried leaves, stems, and seeds of the cannabis Sativa, Indica, and Ruderalis plants. The two active components in marijuana are delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD).

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